A 22-year-old woman is taking isoniazid prophylaxis for tuberculosis exposure. After 1 month of therapy she develops tingling in both her hands. What is the term for what she is experiencing and how would you treat her?

A 22-year-old woman is taking isoniazid prophylaxis for tuberculosis exposure. After 1 month of therapy she develops tingling in both her hands. What is the term for what she is experiencing and how would you treat her?


Answer: Peripheral neuropathy due to vitamin B6 depletion by the isoniazid (INH). Treat with vitamin B6, otherwise known as pyridoxine



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